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Multiphoton microscopy

Abstract : Endoscopic examination is a well-established medical practice and helps hospital practitioners to orientate diagnostic and treatments with a painless protocol which also contributes to improve the care of patients. But the endoscopic images generated are restrained to a surface imaging and image quality is limited to a millimetric resolution. The precision of the diagnostic can be impacted by these restrictions and some significant alteration of the structure, metabolism or physiology of organs can be missed. Today, many technical developments are in progress for the development of endomicroscopes. That imposes for example to resort to the intermediary of an optical waveguide whose internal structure imposes many technical and computational constraints, discussed in the present article. The miniaturization of distal optics or scanning devices are still in progress of elaboration simultaneously with an optimal computational strategy for erasing image defaults linked to the necessity of extremal miniaturization.
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https://hal.archives-ouvertes.fr/hal-03233069
Contributor : Claire Lefort <>
Submitted on : Wednesday, July 7, 2021 - 2:30:25 PM
Last modification on : Thursday, September 2, 2021 - 12:48:03 PM

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Claire Lefort. Multiphoton microscopy. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 1: Part I: Ex vivo biological imaging, IOP Publishing, 2021, ⟨10.1088/978-0-7503-3059-6ch9⟩. ⟨hal-03233069⟩

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